Annotation Detail
Information
- Associated Genes
- HNF4A
- Associated Variants
-
rs1884613
rs2144908 ( ENST00000316673.9, ENST00000457232.5, ENST00000609795.5 )
rs1884613
rs2144908 ( ENST00000316673.9, ENST00000457232.5, ENST00000609795.5 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- HNF4A promoter P2 polymorphisms rs1884613 and rs2144908, which are in high linkage disequilibrium, showed significant association with type 2 diabetes (odds ratio (OR)=1.37 (95% confidence interval (CI) 1.19-1.57), P=9.4 × 10(-6) for rs1884613 and OR=1.37 (95%CI 1.20-1.57), P=6.0 × 10(-6) for rs2144908), as previously shown in other populations.
- Pubmed
- 21814221
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.60754205370071
- Year of publication
- 2011
Drugs