Annotation Detail
Information
- Associated Genes
- CD40LG
- Associated Variants
-
CD40 p.Met1= (p.M1=)
(
ENST00000372276.7,
ENST00000372285.8,
ENST00000695671.1 )
CD40 p.Met1= (p.M1=) ( ENST00000372276.7, ENST00000372285.8, ENST00000695671.1 ) - Associated Disease
- lymphoma
- Source Database
- DisGeNET
- Description
- We hypothesized that single nucleotide polymorphisms (SNPs) in TNFRSF5 and TNFSF5 encoding the CD40 and CD154 proteins, respectively, influence lymphoma risk, particularly a functional TNFRSF5 SNP (-1C>T, rs1883832) associated with reduced B-cell CD40 expression.
- Pubmed
- 18287517
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00380018620912425
- Year of publication
- 2008
Drugs