Annotation Detail

Information
Associated Genes
TNF
Associated Variants
rs352162
rs187084
rs352162
rs187084
Associated Disease
Sepsis
Source Database
DisGeNET
Description
Both rs187084 and rs352162 were significantly associated with TNF-α production by peripheral blood leucocytes in response to bacterial DNA stimulation and a higher sepsis morbidity rate in patients with major trauma.
Pubmed
21633947
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.286154284236114
Year of publication
2011
Drugs