Annotation Detail
Information
- Associated Genes
- POU5F1B
- Associated Variants
-
rs944289
EPHB1 c.1298-6543C>G ( ENST00000398015.8, ENST00000493838.1, ENST00000647596.1 )
rs6983267 ( ENST00000645438.1 )
rs2439302 ( ENST00000287842.7, ENST00000356819.7, ENST00000405005.8, ENST00000519301.6, ENST00000520407.5, ENST00000521670.5, ENST00000523079.5, ENST00000650919.1, ENST00000650967.1, ENST00000650980.1, ENST00000652588.1, ENST00000652698.1 )
FOXE1 c.-283A>G ( ENST00000375123.5 )
rs944289
EPHB1 c.1298-6543C>G ( ENST00000398015.8, ENST00000493838.1, ENST00000647596.1 )
rs6983267 ( ENST00000645438.1 )
rs2439302 ( ENST00000287842.7, ENST00000356819.7, ENST00000405005.8, ENST00000519301.6, ENST00000520407.5, ENST00000521670.5, ENST00000523079.5, ENST00000650919.1, ENST00000650967.1, ENST00000650980.1, ENST00000652588.1, ENST00000652698.1 )
FOXE1 c.-283A>G ( ENST00000375123.5 ) - Associated Disease
- Papillary thyroid carcinoma
- Source Database
- DisGeNET
- Description
- In a multicenter retrospective case-control study, five thyroid cancer-related SNPs-rs966513 (9q22.33, FOXE1), rs944289 (14q13.3, PTCSC3), rs2439302 (8p12, NRG1), rs1867277 (9q22.23, FOXE1), and rs6983267 (8q24, POU5F1B)-were genotyped in 959 cases of histologically verified FA, 535 papillary thyroid carcinomas (PTC), and 2766 population controls.
- Pubmed
- 25562676
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2015
Drugs