Annotation Detail

Information
Associated Genes
CDKN2A
Associated Variants
CDKN2A p.Met53Ile (p.M53I) ( ENST00000304494.10, ENST00000479692.2, ENST00000494262.5, ENST00000497750.1, ENST00000498124.1, ENST00000498628.6, ENST00000530628.2, ENST00000578845.2, ENST00000579122.1, ENST00000579755.2 )
CDKN2A p.Met53Ile (p.M53I) ( ENST00000579755.2, ENST00000498628.6, ENST00000578845.2, ENST00000494262.5, ENST00000530628.2, ENST00000498124.1, ENST00000497750.1, ENST00000479692.2, ENST00000579122.1, ENST00000304494.10 )
CDKN2A p.Met53Ile (p.M53I) ( ENST00000578845.2, ENST00000579122.1, ENST00000579755.2, ENST00000304494.10, ENST00000479692.2, ENST00000494262.5, ENST00000497750.1, ENST00000498124.1, ENST00000498628.6, ENST00000530628.2 )
CDKN2A p.Met53Ile (p.M53I) ( ENST00000304494.10, ENST00000479692.2, ENST00000494262.5, ENST00000497750.1, ENST00000498124.1, ENST00000498628.6, ENST00000530628.2, ENST00000578845.2, ENST00000579122.1, ENST00000579755.2 )
Associated Disease
melanoma
Source Database
DisGeNET
Description
The M53I mutation in CDKN2A is a founder mutation that predominates in melanoma patients with Scottish ancestry.
Pubmed
17171691
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.36
Year of publication
2007
Drugs