Annotation Detail

Information
Associated Genes
CDKN2A
Associated Variants
CDKN2A p.Gly101Trp (p.G101W) ( ENST00000498124.1, ENST00000497750.1, ENST00000579122.1, ENST00000494262.5, ENST00000579755.2, ENST00000530628.2, ENST00000498628.6, ENST00000578845.2, ENST00000304494.10, ENST00000479692.2 )
CDKN2A p.Gly101Arg (p.G101R) ( ENST00000497750.1, ENST00000498124.1, ENST00000498628.6, ENST00000530628.2, ENST00000578845.2, ENST00000579122.1, ENST00000579755.2, ENST00000304494.10, ENST00000479692.2, ENST00000494262.5 )
CDKN2A p.Gly101Trp (p.G101W) ( ENST00000304494.10, ENST00000498628.6, ENST00000578845.2, ENST00000579122.1, ENST00000579755.2, ENST00000479692.2, ENST00000494262.5, ENST00000497750.1, ENST00000498124.1, ENST00000530628.2 )
CDKN2A p.Gly101Arg (p.G101R) ( ENST00000304494.10, ENST00000479692.2, ENST00000494262.5, ENST00000497750.1, ENST00000498124.1, ENST00000498628.6, ENST00000530628.2, ENST00000578845.2, ENST00000579122.1, ENST00000579755.2 )
Associated Disease
Dysplastic Nevus
Source Database
DisGeNET
Description
Among patients with melanoma genetically tested, CDKN2A G101W mutation carriers were more frequently younger (P = 0.023), with clinically atypical nevi (P = 0.050), with cytological atypia (P = 0.033) at confocal.
Pubmed
23711066
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00671010193188688
Year of publication
2013
Drugs