Annotation Detail
Information
- Associated Genes
- XRCC4
- Associated Variants
-
XRCC4 c.894-1G>A
(
ENST00000282268.7,
ENST00000338635.10,
ENST00000396027.9,
ENST00000511817.1 )
XRCC4 c.894-1G>A ( ENST00000282268.7, ENST00000338635.10, ENST00000396027.9, ENST00000511817.1 ) - Associated Disease
- liver carcinoma
- Source Database
- DisGeNET
- Description
- The SNP of XRCC4 rs1805377 was significantly associated with decreased risk of HCC development (OR, 0.592; p=0.028) and improved overall survival of patients with HCC (median survival time (MST) of 48, 72, and 89 months for the AA, AG, and GG genotypes, respectively; p=0.044).
- Pubmed
- 22659345
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2012
Drugs