Annotation Detail
Information
- Associated Genes
- IRS1
- Associated Variants
-
IRS1 MUTATION
IRS1 MUTATION - Associated Disease
- progressive supranuclear palsy
- Source Database
- DisGeNET
- Description
- IRS1-pS(616), IRS1-pS(312) and downstream target Akt-pS(473) measures were most elevated in AD but were also significantly increased in the tauopathies: Pick's disease, corticobasal degeneration and progressive supranuclear palsy.
- Pubmed
- 25107476
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs