Annotation Detail

Information
Associated Genes
KCNE1
Associated Variants
KCNE1 p.Asp85Asn (p.D85N) ( ENST00000416357.6, ENST00000399284.1, ENST00000399286.3, ENST00000337385.7, ENST00000399289.7, ENST00000432085.5, ENST00000611936.1, ENST00000621601.4 )
KCNE1 p.Asp85Asn (p.D85N) ( ENST00000337385.7, ENST00000399284.1, ENST00000399286.3, ENST00000399289.7, ENST00000416357.6, ENST00000432085.5, ENST00000611936.1, ENST00000621601.4 )
Associated Disease
Tachycardia
Source Database
DisGeNET
Description
During the tachycardia phase following adenosine, QTc increased to 620 ms. Genetic analysis revealed a rare heterozygous polymorphism in KCNE1 predicting the substitution of asparagine for aspartic acid at position 85 of minK (D85N).
Pubmed
21712262
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2011
Drugs