Annotation Detail

Information
Associated Genes
CACNA1C
Associated Variants
CACNA1C MUTATION
CACNA1C MUTATION
Associated Disease
substance dependence
Source Database
DisGeNET
Description
With regard to the molecular mechanisms underlying drug addiction, Cav1.3 channels are necessary for the development and Cav1.2 channels for the expression of cocaine and amphetamine behavioural sensitisation.
Pubmed
24996399
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs