Annotation Detail
Information
- Associated Genes
- IRS2
- Associated Variants
-
IRS2 p.Gly1057Asp (p.G1057D)
(
ENST00000375856.5 )
IRS2 p.Gly1057Asp (p.G1057D) ( ENST00000375856.5 ) - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- In conclusion, in our elderly subjects the presence of the allelic variant Gly1057Asp of IRS2 gene was associated to the degree of insulin resistance assessed by HOMA index and with EpiF thickness, independently from the extent of obesity, suggesting its contribution to global cardiometabolic risk.
- Pubmed
- 23018177
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0146255234839339
- Year of publication
- 2012
Drugs