Annotation Detail

Information
Associated Genes
IRS2
Associated Variants
IRS2 p.Gly1057Asp (p.G1057D) ( ENST00000375856.5 )
IRS2 p.Gly1057Asp (p.G1057D) ( ENST00000375856.5 )
Associated Disease
Obesity, Morbid
Source Database
DisGeNET
Description
Complex haplotypes of IRS2 gene are associated with severe obesity and reveal heterogeneity in the effect of Gly1057Asp mutation.
Pubmed
12687350
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2003
Drugs