Annotation Detail

Information
Associated Genes
LEP
Associated Variants
LEPR p.Pro1019= (p.P1019=) ( ENST00000349533.11 )
RS1 c.52+4364G>A ( ENST00000379984.4 )
LEPR p.Pro1019= (p.P1019=) ( ENST00000349533.11 )
RS1 c.52+4364G>A ( ENST00000379984.4 )
Associated Disease
obesity
Source Database
DisGeNET
Description
The aim of this study was to evaluate the effect of the G3057A (rs62589000) LEPR polymorphism on obesity risk and plasma leptin, insulin, and lipid levels in a sample of the Tunisian population.
Pubmed
20304616
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.44
Year of publication
2011
Drugs