Annotation Detail

Information
Associated Genes
SHMT1
Associated Variants
SHMT1 p.Leu474Phe (p.L474F) ( ENST00000316694.8, ENST00000354098.7 )
MTR p.Leu474= (p.L474=) ( ENST00000681177.1, ENST00000366577.10, ENST00000535889.6, ENST00000681102.1, ENST00000674797.2, ENST00000679842.1 )
MTR p.Asp919Gly (p.D919G) ( ENST00000366577.10, ENST00000535889.6, ENST00000681177.1, ENST00000681102.1, ENST00000679842.1, ENST00000674797.2 )
SHMT1 p.Leu474Phe (p.L474F) ( ENST00000316694.8, ENST00000354098.7 )
MTR p.Leu474= (p.L474=) ( ENST00000366577.10, ENST00000535889.6, ENST00000674797.2, ENST00000679842.1, ENST00000681102.1, ENST00000681177.1 )
MTR p.Asp919Gly (p.D919G) ( ENST00000366577.10, ENST00000535889.6, ENST00000674797.2, ENST00000679842.1, ENST00000681102.1, ENST00000681177.1 )
Associated Disease
Malignant neoplasm of prostate
Source Database
DisGeNET
Description
Role of polymorphic variants of MTR gene A2756G and SHMT1 gene C1420T in the development of prostatic cancer in residents of the Western Siberian Region of Russia.
Pubmed
22803112
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00554838957344497
Year of publication
2012
Drugs