Annotation Detail

Information
Associated Genes
MSTN
Associated Variants
MSTN p.Lys153Arg (p.K153R) ( ENST00000260950.5 )
MSTN p.Lys153Arg (p.K153R) ( ENST00000260950.5 )
Associated Disease
obesity
Source Database
DisGeNET
Description
Recent studies demonstrated an association between the K153R polymorphism in the myostatin gene with extreme longevity, lower muscle strength and obesity but the molecular basis of these associations has not been clarified.
Pubmed
25543063
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Year of publication
2014
Drugs