Annotation Detail

Information
Associated Genes
PALB2
Associated Variants
PALB2 p.Leu531CysfsTer30 (p.L531Cfs*30) ( ENST00000566069.6, ENST00000697379.2, ENST00000261584.9, ENST00000697376.1, ENST00000561514.3, ENST00000697383.1, ENST00000568219.5, ENST00000697374.1, ENST00000697377.2, ENST00000713774.1 )
PALB2 p.Leu531CysfsTer30 (p.L531Cfs*30) ( ENST00000261584.9, ENST00000561514.3, ENST00000566069.6, ENST00000568219.5, ENST00000697374.1, ENST00000697376.1, ENST00000697377.2, ENST00000697379.2, ENST00000697383.1, ENST00000713774.1 )
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
Evaluation of the need for routine clinical testing of PALB2 c.1592delT mutation in BRCA negative Northern Finnish breast cancer families.
Pubmed
23941127
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0625737220169401
Year of publication
2013
Drugs