Annotation Detail

Information
Associated Genes
BRAF
Associated Variants
BRAF p.Asn621Asp (p.N621D) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 )
BRAF p.Asn621His (p.N621H) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 )
BRAF p.Asn621Asp (p.N621D) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 )
BRAF p.Asn621His (p.N621H) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 )
Associated Disease
Cardio-facio-cutaneous syndrome
Source Database
DisGeNET
Description
In this case report, we present a male CFCS patient with tight Achilles tendons with a de-novo heterozygote N581D mutation in the BRAF gene detected by DNA sequence analysis.
Pubmed
22876591
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.567057488674088
Year of publication
2012
Drugs