Annotation Detail
Information
- Associated Genes
- HLA-E
- Associated Variants
-
HLA-E MUTATION
HLA-E MUTATION - Associated Disease
- ankylosing spondylitis
- Source Database
- DisGeNET
- Description
- The human MHC class I protein HLA-B*27:05 is statistically associated with ankylosing spondylitis, unlike HLA-B*27:09, which differs in a single amino acid in the F pocket of the peptide-binding groove.
- Pubmed
- 25615938
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0105102881410111
Drugs