Annotation Detail

Information
Associated Genes
MTNR1B
Associated Variants
MTNR1B MUTATION
MTNR1B MUTATION
Associated Disease
Sleep disturbances
Source Database
DisGeNET
Description
These studies demonstrate that MT2 receptors are involved in the pathophysiology and pharmacology of sleep disorders, anxiety, depression, Alzheimer disease and pain and that selective MT2 receptor agonists show hypnotic and anxiolytic properties.
Pubmed
23971978
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs