Annotation Detail
Information
- Associated Genes
- DNMT1
- Associated Variants
-
DNMT1 p.Ile327Phe (p.I327F)
(
ENST00000340748.8,
ENST00000359526.9,
ENST00000676610.1,
ENST00000677946.1,
ENST00000678804.1,
ENST00000679103.1,
ENST00000679313.1 )
DNMT1 p.Ile327Val (p.I327V) ( ENST00000340748.8, ENST00000359526.9, ENST00000676610.1, ENST00000677946.1, ENST00000678804.1, ENST00000679103.1, ENST00000679313.1 )
DNMT1 p.Ile327Leu (p.I327L) ( ENST00000340748.8, ENST00000359526.9, ENST00000676610.1, ENST00000677946.1, ENST00000678804.1, ENST00000679103.1, ENST00000679313.1 )
MTRR p.Ile22Met (p.I22M) ( ENST00000264668.6, ENST00000440940.7 )
DNMT1 p.Ile327Phe (p.I327F) ( ENST00000340748.8, ENST00000359526.9, ENST00000676610.1, ENST00000677946.1, ENST00000678804.1, ENST00000679103.1, ENST00000679313.1 )
DNMT1 p.Ile327Val (p.I327V) ( ENST00000340748.8, ENST00000359526.9, ENST00000676610.1, ENST00000677946.1, ENST00000678804.1, ENST00000679103.1, ENST00000679313.1 )
DNMT1 p.Ile327Leu (p.I327L) ( ENST00000340748.8, ENST00000359526.9, ENST00000676610.1, ENST00000677946.1, ENST00000678804.1, ENST00000679103.1, ENST00000679313.1 )
MTRR p.Ile22Met (p.I22M) ( ENST00000264668.6, ENST00000440940.7 ) - Associated Disease
- Malignant tumor of colon
- Source Database
- DisGeNET
- Description
- However, statistically significant interactions modifying CC risk were observed for DNMT1 I311V with dietary folate, methionine, vitamin B2 , and vitamin B12 intake and for MTRR I22M with dietary folate, a predefined one-carbon dietary pattern, and vitamin B6 intake.
- Pubmed
- 22961839
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00325730246496364
- Year of publication
- 2013
Drugs