Annotation Detail

Information
Associated Genes
LEP
Associated Variants
LEP p.Arg105Trp (p.R105W) ( ENST00000308868.5 )
LEP p.Arg105Trp (p.R105W) ( ENST00000308868.5 )
Associated Disease
LEPTIN DEFICIENCY OR DYSFUNCTION
Source Database
DisGeNET
Description
A leptin missense mutation associated with hypogonadism and morbid obesity.
Pubmed
9500540
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.367600372418248
Year of publication
1998
Drugs