Annotation Detail

Information
Associated Genes
MTHFR
Associated Variants
MTRR p.Ile22Met (p.I22M) ( ENST00000264668.6, ENST00000440940.7 )
MTRR p.Ile22Met (p.I22M) ( ENST00000264668.6, ENST00000440940.7 )
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
In addition, we found interactions between the MTRR A66G polymorphism and smoking (P = 0.015) and the MTHFR A1,298C polymorphism and alcohol consumption (P = 0.025) for risk of lung cancer overall.
Pubmed
17468511
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0567651602247305
Year of publication
2007
Drugs