Annotation Detail

Information
Associated Genes
BRCA2
Associated Variants
RAD51 c.-98G>C ( ENST00000382643.7, ENST00000423169.6, ENST00000557850.5, ENST00000645673.2, ENST00000267868.8 )
RAD51 c.-98G>C ( ENST00000267868.8, ENST00000382643.7, ENST00000423169.6, ENST00000557850.5, ENST00000645673.2 )
Associated Disease
breast carcinoma
Source Database
DisGeNET
Description
A single-nucleotide polymorphism (SNP) in the 5'-untranslated region (UTR) of RAD51, 135G>C (rs1801320), was reported to be associated with an increased risk of breast cancer among BRCA2 as well as BRCA1 carriers.
Pubmed
20461453
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.08
Year of publication
2011
Drugs