Annotation Detail
Information
- Associated Genes
- TERT
- Associated Variants
-
TERT c.1951-205G>A
(
ENST00000310581.10,
ENST00000334602.10 )
TERT c.1951-205G>A ( ENST00000310581.10, ENST00000334602.10 ) - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- Associations with TN breast cancer were confirmed for 10 loci (LGR6, MDM4, CASP8, 2q35, 2p24.1, TERT-rs10069690, ESR1, TOX3, 19p13.1, RALY), and we identified associations with TN breast cancer for 15 additional breast cancer loci (P < 0.05: PEX14, 2q24.1, 2q31.1, ADAM29, EBF1, TCF7L2, 11q13.1, 11q24.3, 12p13.1, PTHLH, NTN4, 12q24, BRCA2, RAD51L1-rs2588809, MKL1).
- Pubmed
- 24325915
- Original source reporting the Gene Disease association
- GWASCAT
- DisGENET score for the Gene Disease association
- 0.138425709693058
- Year of publication
- 2014
Drugs