Annotation Detail
Information
- Associated Genes
- IRS1
- Associated Variants
-
IRS1 p.Gly971Trp (p.G971W)
(
ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
IRS1 p.Gly971Trp (p.G971W) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 ) - Associated Disease
- diabetes mellitus
- Source Database
- DisGeNET
- Description
- The most common single-nucleotide polymorphism in the insulin receptor substrate-1 (IRS1) gene is Gly972Arg, which is associated with a 25% increased risk of developing diabetes.
- Pubmed
- 25214251
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.128610195036449
- Year of publication
- 2013
Drugs