Annotation Detail

Information
Associated Genes
IRS2
Associated Variants
IRS2 p.Gly1057Asp (p.G1057D) ( ENST00000375856.5 )
IRS1 p.Gly971Trp (p.G971W) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
IRS2 p.Gly1057Asp (p.G1057D) ( ENST00000375856.5 )
IRS1 p.Gly971Trp (p.G971W) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
Associated Disease
polycystic ovary syndrome
Source Database
DisGeNET
Description
Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome.
Pubmed
11522686
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0114540974107551
Year of publication
2001
Drugs