Annotation Detail

Information
Associated Genes
IRS1
Associated Variants
IRS1 p.Gly971Trp (p.G971W) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
CAPN10 c.471-176G>A ( ENST00000270364.11, ENST00000352879.8, ENST00000354082.8, ENST00000391984.7, ENST00000404753.7 )
IRS1 p.Gly971Trp (p.G971W) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
IRS1 p.Gly971Arg (p.G971R) ( ENST00000305123.6 )
CAPN10 c.471-176G>A ( ENST00000270364.11, ENST00000352879.8, ENST00000354082.8, ENST00000391984.7, ENST00000404753.7 )
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
We replicated the significant association of rs1801278 and rs3792267 SNPs of the IRS1 and CAPN10 genes with T2DM in the population of Hyderabad.
Pubmed
24612564
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.62714418720803
Year of publication
2014
Drugs