Annotation Detail
Information
- Associated Genes
- IL4R
- Associated Variants
-
IL4R p.Gln576Arg (p.Q576R)
(
ENST00000543915.6,
ENST00000170630.6,
ENST00000395762.7 )
MAP3K1 p.Asp806Asn (p.D806N) ( ENST00000399503.4 )
IL4R p.Gln576Arg (p.Q576R) ( ENST00000170630.6, ENST00000395762.7, ENST00000543915.6 )
MAP3K1 p.Asp806Asn (p.D806N) ( ENST00000399503.4 ) - Associated Disease
- Wheezing
- Source Database
- DisGeNET
- Description
- Interestingly, the study of gene-environment interactions showed that rhinovirus was significantly associated with recurrent wheezing in the presence of IL4Ra-rs1801275GG and G (odds ratio [OR] 6.03, 95% confidence interval [CI]: 1.21-30.10, p = 0.03) and MAP3K1-rs702689AA (OR 4.09, 95% CI: 1.14-14.61, p = 0.03).
- Pubmed
- 25326706
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00135720936040152
- Year of publication
- 2014
Drugs