Annotation Detail
Information
- Associated Genes
- IL4R
- Associated Variants
-
IL4R p.Gln576Arg (p.Q576R)
(
ENST00000543915.6,
ENST00000170630.6,
ENST00000395762.7 )
IL4R p.Gln576Arg (p.Q576R) ( ENST00000170630.6, ENST00000395762.7, ENST00000543915.6 ) - Associated Disease
- asthma
- Source Database
- DisGeNET
- Description
- Our findings indicate that the Q576R polymorphism directly promotes asthma in carrier populations by selectively augmenting IL-4R alpha-dependent signaling.
- Pubmed
- 19770271
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.111013894068804
- Year of publication
- 2009
Drugs