Annotation Detail

Information
Associated Genes
MDM2
Associated Variants
CDKN1A p.Ser31Arg (p.S31R) ( ENST00000244741.10, ENST00000373711.3, ENST00000405375.5, ENST00000448526.6, ENST00000615513.4 )
CDKN1A p.Ser31= (p.S31=) ( ENST00000244741.10, ENST00000373711.3, ENST00000405375.5, ENST00000448526.6, ENST00000615513.4 )
CDKN1A p.Ser31Arg (p.S31R) ( ENST00000244741.10, ENST00000373711.3, ENST00000405375.5, ENST00000448526.6, ENST00000615513.4 )
CDKN1A p.Ser31= (p.S31=) ( ENST00000244741.10, ENST00000373711.3, ENST00000405375.5, ENST00000448526.6, ENST00000615513.4 )
Associated Disease
Leukemia, Myelocytic, Acute
Source Database
DisGeNET
Description
MDM2 T309G has a synergistic effect with P21 ser31arg single nucleotide polymorphisms on the risk of acute myeloid leukemia.
Pubmed
23167335
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0117915526312919
Year of publication
2012
Drugs