Annotation Detail
Information
- Associated Genes
- EIF4EBP1
- Associated Variants
-
EIF4EBP1 MUTATION
EIF4EBP1 MUTATION - Associated Disease
- Rift Valley fever
- Source Database
- DisGeNET
- Description
- We find that the RNA decapping enzyme NUDT16 selectively degrades 5'-TOP mRNAs during RVFV infection and this decay is triggered in response to mTOR attenuation via the translational repressor 4EBP1/2 axis.
- Pubmed
- 26038567
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs