Annotation Detail

Information
Associated Genes
BDNF
Associated Variants
BDNF MUTATION
BDNF MUTATION
Associated Disease
Rett syndrome
Source Database
DisGeNET
Description
Lack of microglial phagocytosis and decreased levels of BDNF appear to distinguish Rett syndrome from ASDs, in which there is instead microglia activation and/or proliferation and possibly defective BDNF signaling.
Pubmed
25669997
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0109871585367152
Drugs