Annotation Detail

Information
Associated Genes
HLA-DRB1
Associated Variants
HLA-DRB1 MUTATION
HLA-DRB1 MUTATION
Associated Disease
kidney failure
Source Database
DisGeNET
Description
Human leukocyte antigen (HLA) gene typing showed DRB1*1501, an allele strongly associated with anti-GBM disease, and DRB1*0405, an independent risk factor for renal failure in patients with ANCA-associated vasculitis.
Pubmed
26200622
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Drugs