Annotation Detail

Information
Associated Genes
AGT
Associated Variants
AGT MUTATION
AGT MUTATION
Associated Disease
kidney failure
Source Database
DisGeNET
Description
We isolated transgenic BMSCs (TG-BMSCs) from young end-organ-disease-free rats with increased RAS activation [human angiotensinogen/renin double transgenic rats (dTGRs)] that eventually develop hypertension and die of end-organ damage and kidney failure at 8 weeks of age.
Pubmed
25534858
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0104343432708904
Drugs