Annotation Detail

Information
Associated Genes
DRD4
Associated Variants
rs936461
rs1800955
rs936461
rs1800955
Associated Disease
Psychotic Disorders
Source Database
DisGeNET
Description
Linkage between the DRD4 and COMT genes and cognitive measures characterizing verbal memory, executive functions, and associative processes was studied in 150 patients with schizophrenia, 83 of their relatives, and 118 mentally healthy subjects without any family history of psychoses, with the aim of detecting the main effects of the polymorphic markers -809G/A and -521C/T (DRD4) and Val158Met (COMT) when present individually and together.
Pubmed
17763983
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0135397559956127
Year of publication
2007
Drugs