Annotation Detail
Information
- Associated Genes
- TLR2
- Associated Variants
-
rs1891320
IL19 c.-149+2474T>C ( ENST00000656872.2, ENST00000659642.2, ENST00000659997.3, ENST00000664374.2, ENST00000659065.2 )
TLR5 c.-555+461C>G ( ENST00000407096.7, ENST00000645434.2, ENST00000714229.1, ENST00000642603.2, ENST00000484766.2 )
TLR2 p.Asn199= (p.N199=) ( ENST00000260010.7, ENST00000642580.1, ENST00000642700.2, ENST00000643501.2, ENST00000646219.2, ENST00000646900.2, ENST00000714431.1, ENST00000714432.1, ENST00000714433.1, ENST00000714434.1, ENST00000714435.1, ENST00000714436.1 )
rs1891320
IL19 c.-149+2474T>C ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
TLR5 c.-555+461C>G ( ENST00000407096.7, ENST00000484766.2, ENST00000642603.2, ENST00000645434.2, ENST00000714229.1 )
TLR2 p.Asn199= (p.N199=) ( ENST00000260010.7, ENST00000642580.1, ENST00000642700.2, ENST00000643501.2, ENST00000646219.2, ENST00000646900.2, ENST00000714431.1, ENST00000714432.1, ENST00000714433.1, ENST00000714434.1, ENST00000714435.1, ENST00000714436.1 ) - Associated Disease
- Sepsis
- Source Database
- DisGeNET
- Description
- Polymorphisms in TLR2 (rs3804099), TLR5 (rs5744105), IL10 (rs1800896), and PLA2G2A (rs1891320) genes were associated with sepsis.
- Pubmed
- 20463618
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0999024711852986
- Year of publication
- 2010
Drugs