Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
IL10 c.379-474C>T
(
ENST00000659642.2,
ENST00000423557.1,
ENST00000664374.2,
ENST00000659065.2,
ENST00000471071.2 )
IL10 c.379-474C>G ( ENST00000471071.2, ENST00000659065.2, ENST00000664374.2, ENST00000423557.1, ENST00000659642.2 )
IL10 c.166-286G>T ( ENST00000423557.1, ENST00000656872.2, ENST00000659642.2, ENST00000659997.3, ENST00000659065.2, ENST00000664374.2 )
IL19 c.-149+2474T>C ( ENST00000656872.2, ENST00000659642.2, ENST00000659997.3, ENST00000664374.2, ENST00000659065.2 )
IL10 c.379-474C>T ( ENST00000423557.1, ENST00000471071.2, ENST00000659065.2, ENST00000659642.2, ENST00000664374.2 )
IL10 c.379-474C>G ( ENST00000423557.1, ENST00000471071.2, ENST00000659065.2, ENST00000659642.2, ENST00000664374.2 )
IL10 c.166-286G>T ( ENST00000423557.1, ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
IL19 c.-149+2474T>C ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 ) - Associated Disease
- Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
- Source Database
- DisGeNET
- Description
- Eight single nucleotide polymorphisms were associated with spontaneous production of IL-10 in culture, of which three (rs1800896 and rs1878672, p = .04; rs3024491, p = .01) were strongly associated with infection by Helicobacter pylori.
- Pubmed
- 24628819
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00407162808120455
- Year of publication
- 2014
Drugs