Annotation Detail

Information
Associated Genes
TLR2
Associated Variants
rs1891320
IL19 c.-149+2474T>C ( ENST00000656872.2, ENST00000659642.2, ENST00000659997.3, ENST00000664374.2, ENST00000659065.2 )
TLR5 c.-555+461C>G ( ENST00000407096.7, ENST00000645434.2, ENST00000714229.1, ENST00000642603.2, ENST00000484766.2 )
TLR2 p.Asn199= (p.N199=) ( ENST00000260010.7, ENST00000642580.1, ENST00000642700.2, ENST00000643501.2, ENST00000646219.2, ENST00000646900.2, ENST00000714431.1, ENST00000714432.1, ENST00000714433.1, ENST00000714434.1, ENST00000714435.1, ENST00000714436.1 )
rs1891320
IL19 c.-149+2474T>C ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
TLR5 c.-555+461C>G ( ENST00000407096.7, ENST00000484766.2, ENST00000642603.2, ENST00000645434.2, ENST00000714229.1 )
TLR2 p.Asn199= (p.N199=) ( ENST00000260010.7, ENST00000642580.1, ENST00000642700.2, ENST00000643501.2, ENST00000646219.2, ENST00000646900.2, ENST00000714431.1, ENST00000714432.1, ENST00000714433.1, ENST00000714434.1, ENST00000714435.1, ENST00000714436.1 )
Associated Disease
Septicemia
Source Database
DisGeNET
Description
Polymorphisms in TLR2 (rs3804099), TLR5 (rs5744105), IL10 (rs1800896), and PLA2G2A (rs1891320) genes were associated with sepsis.
Pubmed
20463618
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00542883744160607
Year of publication
2010
Drugs