Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
IL19 c.-149+2474T>C
(
ENST00000656872.2,
ENST00000659642.2,
ENST00000659997.3,
ENST00000664374.2,
ENST00000659065.2 )
IL19 c.-149+2474T>C ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 ) - Associated Disease
- Malignant neoplasm of prostate
- Source Database
- DisGeNET
- Description
- [Using Multivariate Adaptive Regression Splines modeling for exploratory SNP-SNP interactions, our results showed that more aggressive PCa in Caucasians Americans is associated with the CT genotype at IL8-47 odds ratios (OR) = 3.50; 95% CI = 1.13-10.88 or combined genotypes of IL1B-511CC and IL10-1082GG (OR = 3.38; 95% CI = 1.70-6.71).]
- Pubmed
- 19474090
- Original source reporting the Gene Disease association
- GAD
- DisGENET score for the Gene Disease association
- 0.0353859275471916
- Year of publication
- 2009
Drugs