Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
rs1800890
(
ENST00000659997.3,
ENST00000656872.2 )
rs1800890 ( ENST00000656872.2, ENST00000659997.3 ) - Associated Disease
- diffuse large B-cell lymphoma
- Source Database
- DisGeNET
- Description
- Compared with women who were never occupationally exposed to any organic solvents, women who were exposed to organic solvents at least once had a significantly increased risk for diffuse large B-cell lymphoma if they carried the IL10 (rs1800890) TT genotype (odds ratio=3.31, 95% confidence interval: 1.80-6.08), but not if they carried the AT/AA genotype (odds ratio=1.14, 95% confidence interval: 0.72-1.79).
- Pubmed
- 22609637
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.016178229846295
- Year of publication
- 2013
Drugs