Annotation Detail

Information
Associated Genes
ADRB2
Associated Variants
ADRB2 p.Thr164Ile (p.T164I) ( ENST00000305988.6 )
ADRB2 p.Thr164Ile (p.T164I) ( ENST00000305988.6 )
Associated Disease
Cardiomyopathy, Dilated
Source Database
DisGeNET
Description
It has been suggested that patients with chronic heart failure (CHF) due to ischemic or dilated cardiomyopathy carrying the Thr164Ile-beta(2)AR polymorphism exhibit much more rapid progression to death or heart transplantation (HTX) than CHF-patients carrying the homozygous Thr164-beta(2)AR.
Pubmed
16783489
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.212735361901036
Year of publication
2006
Drugs