Annotation Detail
Information
- Associated Genes
- HLA-DQB1
- Associated Variants
-
NC_000019.10:g.39252525T>G
IL19 c.-149+1984T>G ( ENST00000659642.2, ENST00000659997.3, ENST00000656872.2, ENST00000659065.2, ENST00000664374.2 )
IL19 c.-149+2211A>G ( ENST00000664374.2, ENST00000659065.2, ENST00000659642.2, ENST00000659997.3, ENST00000656872.2 )
rs2856718
HLA-DQB2 c.98-309T>C ( ENST00000411527.5, ENST00000435145.6, ENST00000437316.7 )
HLA-DPA1 c.*115T>C ( ENST00000419277.5, ENST00000692443.1 )
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000428835.6, ENST00000418931.7 )
NC_000019.10:g.39252525T>G
IL19 c.-149+1984T>G ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
IL19 c.-149+2211A>G ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
rs2856718
HLA-DQB2 c.98-309T>C ( ENST00000411527.5, ENST00000435145.6, ENST00000437316.7 )
HLA-DPA1 c.*115T>C ( ENST00000419277.5, ENST00000692443.1 )
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000418931.7, ENST00000428835.6 ) - Associated Disease
- hepatitis B
- Source Database
- DisGeNET
- Description
- This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.
- Pubmed
- 25376093
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0113682210189702
- Year of publication
- 2014
Drugs