Annotation Detail
Information
- Associated Genes
- IL13
- Associated Variants
-
IL19 c.-149+2211A>G
(
ENST00000664374.2,
ENST00000659065.2,
ENST00000659642.2,
ENST00000659997.3,
ENST00000656872.2 )
IL13 p.Gln144Arg (p.Q144R) ( ENST00000304506.7 )
IL19 c.-149+2211A>G ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
IL13 p.Gln144Arg (p.Q144R) ( ENST00000304506.7 ) - Associated Disease
- glioblastoma
- Source Database
- DisGeNET
- Description
- In the genetic model analysis, the genotype TC of rs20541 in IL-13 gene showed an increased risk of GBM in over-dominant model (OR = 2.00; 95% CI, 1.13-3.54, p = 0.015); the genotype CT of rs1800871 in the IL-10 gene showed a decrease risk in the over-dominant model (OR = 0.57; 95% CI, 0.33 - 0.97; p = 0.037).
- Pubmed
- 23663500
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00934857578256922
- Year of publication
- 2013
Drugs