Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
IL19 c.-149+2211A>G
(
ENST00000664374.2,
ENST00000659065.2,
ENST00000659642.2,
ENST00000659997.3,
ENST00000656872.2 )
IL19 c.-149+2211A>G ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 ) - Associated Disease
- Malignant neoplasm of oropharynx
- Source Database
- DisGeNET
- Description
- After adjusting for age, education, ethnicity, gender, and tobacco smoking, IL10 rs1800871 was inversely associated with oropharyngeal cancer (CT+TT vs. CC adjusted odds ratio [aOR]: 0.69, 95% confidence interval [CI]: 0.50-0.95), and was positively associated with lung cancer among never smokers (TT vs. CT+CC aOR: 2.5, 95% CI: 1.3-5.1) and inversely with oropharyngeal cancer among ever smokers (CT+TT vs. CC aOR: 0.63, 95% CI: 0.41-0.95).
- Pubmed
- 20112337
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2010
Drugs