Annotation Detail

Information
Associated Genes
SNCA
Associated Variants
SNCA p.Ala30Pro (p.A30P) ( ENST00000336904.7, ENST00000345009.8, ENST00000394986.5, ENST00000394989.6, ENST00000394991.8, ENST00000420646.6, ENST00000502987.5, ENST00000505199.5, ENST00000506244.5, ENST00000508895.5, ENST00000611107.1, ENST00000618500.4, ENST00000673718.1, ENST00000673902.1, ENST00000674129.1 )
SNCA p.Ala30Pro (p.A30P) ( ENST00000336904.7, ENST00000345009.8, ENST00000394986.5, ENST00000394989.6, ENST00000394991.8, ENST00000420646.6, ENST00000502987.5, ENST00000505199.5, ENST00000506244.5, ENST00000508895.5, ENST00000611107.1, ENST00000618500.4, ENST00000673718.1, ENST00000673902.1, ENST00000674129.1 )
Associated Disease
Parkinson disease
Source Database
DisGeNET
Description
Familial Parkinson disease (PD) due to the A30P mutation in the SNCA gene encoding alpha-synuclein is clinically associated with PD symptoms.
Pubmed
20437567
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.493572093604015
Year of publication
2010
Drugs