Annotation Detail
Information
- Associated Genes
- IGHV3-71
- Associated Variants
-
IL6 c.-85+344A>G
(
ENST00000404625.5 )
IL6 c.-85+344A>G ( ENST00000404625.5 ) - Associated Disease
- hyperglycemia
- Source Database
- DisGeNET
- Description
- Possession of the IL-6 rs1800797 GG genotype by the LTA and TNF-alpha risk genotype carriers further increased risk of the MetS [OR 2.10 (CI 1.19-3.71) P = 0.009], fasting hyperglycemia [OR 2.65 (CI 1.12-6.28), P = 0.027], high systolic blood pressure [OR 1.99 (CI 1.07-3.72), P = 0.03], and abdominal obesity [OR 1.52 (CI 1.01-2.28), P = 0.04].
- Pubmed
- 20080841
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2010
Drugs