Annotation Detail
Information
- Associated Genes
- ZFHX3
- Associated Variants
-
ZFHX3 c.-49-35067A>G
(
ENST00000641206.2,
ENST00000397992.5,
ENST00000268489.10 )
IL6 c.-85+369G>C ( ENST00000404625.5 )
ZFHX3 c.-49-35067A>G ( ENST00000268489.10, ENST00000397992.5, ENST00000641206.2 )
IL6 c.-85+369G>C ( ENST00000404625.5 ) - Associated Disease
- Ischemic stroke
- Source Database
- DisGeNET
- Description
- Nonparametric linkage analysis revealed that the rs1800796 polymorphism in the interleukin-6 (IL-6) gene is significantly linked to the small arterial occlusion (SAO) subtype (p=0.022), while the rs7193343 polymorphism in the ZFHX3 gene is linked to IS (p=0.002) under the dominant model.
- Pubmed
- 25325233
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2015
Drugs