Annotation Detail
Information
- Associated Genes
- ICAM1
- Associated Variants
-
ICAM1 MUTATION
ICAM1 MUTATION - Associated Disease
- pulmonary edema
- Source Database
- DisGeNET
- Description
- Pulmonary vascular barrier function, regulated in part by Src kinase-dependent phosphorylation of caveolin-1 and intercellular adhesion molecule-1 (ICAM-1), plays a crucial role in the development of protein-/neutrophil-rich pulmonary edema, the hallmark of ALI.
- Pubmed
- 25097454
- Section of the abstract supporting the evidence
- BACKGROUND
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs