Annotation Detail
Information
- Associated Genes
- IL6
- Associated Variants
-
IL6 c.-84-153C>G
(
ENST00000404625.5 )
IL6 c.-84-153C>G ( ENST00000404625.5 ) - Associated Disease
- Acute GVH disease
- Source Database
- DisGeNET
- Description
- Similar to previous publications, the IL6 donor genotype for rs1800795 was associated with a 20%-50% increased risk for grade IIb-IV aGVHD after unrelated HCT in the allelic (adjusted P = .011) and recessive (adjusted P = .0013) models.
- Pubmed
- 22282500
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00244297684872273
- Year of publication
- 2012
Drugs