Annotation Detail

Information
Associated Genes
NANOS3
Associated Variants
NOS3 c.-52+1009A>C ( ENST00000297494.8, ENST00000461406.5 )
NOS3 c.-52+1009A>T ( ENST00000297494.8, ENST00000461406.5 )
NOS3 c.-52+1009A>C ( ENST00000297494.8, ENST00000461406.5 )
NOS3 c.-52+1009A>T ( ENST00000297494.8, ENST00000461406.5 )
Associated Disease
Diabetes Mellitus, Insulin-Dependent
Source Database
DisGeNET
Description
The A allele of rs1800783 is a significant risk factor for nephropathy in individuals with type 1 diabetes, and further comprehensive studies are warranted to confirm the definitive functional variant in the NOS3 gene.
Pubmed
20962522
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
2010
Drugs